Set to meet his daughter (Madge Evans) for a dinner party, an attorney (Lionel Barrymore) with a background with both the prosecution and defense informs fellow train travelers just how easy it is, for an intelligent person that is, to get away with murder. When he arrives at the reception. his lascivious friend and client (Alan Mowbray) informs him that he is taking his daughter for his wife come hell or high water, which gives the attorney the opportunity to put his theory to the test. "Guilty Hands" is a silly but fun precode film with Barrymore giving a diverting, animating performance.